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American Society of Microbiology ABMM Exam Syllabus Topics:

SectionObjectives
Topic 1: Infectious Disease Principles- Pathogenesis
  • 1. Mechanisms of microbial infection
    • 2. Host-pathogen interactions
      - Epidemiology
      • 1. Public health microbiology
        • 2. Transmission and outbreak investigation
          Topic 2: Clinical Microbiology- Mycology
          • 1. Medical fungal infections
            • 2. Laboratory identification of fungi
              - Bacteriology
              • 1. Identification and classification of bacterial pathogens
                • 2. Antimicrobial susceptibility testing principles
                  - Virology
                  • 1. Clinical viral pathogens
                    • 2. Diagnostic virology methods
                      - Parasitology
                      • 1. Diagnostic techniques in parasitology
                        • 2. Human parasitic infections
                          Topic 3: Laboratory Management & Quality Systems- Quality assurance and quality control
                          • 1. Laboratory quality systems design
                            • 2. Proficiency testing and validation
                              - Regulatory compliance
                              • 1. Clinical laboratory regulations and accreditation standards
                                • 2. Safety and biosafety requirements
                                  Topic 4: Laboratory Operations- Diagnostic workflow
                                  • 1. Test selection and interpretation
                                    • 2. Specimen handling and processing
                                      - Instrumentation and methodologies
                                      • 1. Molecular diagnostic techniques
                                        • 2. Automated microbiology systems

                                          American Society of Microbiology ABMM Sample Questions:

                                          1. A child presents with a characteristic "slapped cheek" rash followed by a lacy, reticular rash on the trunk and extremities. The causative agent is a single-stranded DNA virus belonging to the family Parvoviridae, known as:

                                          A) Human parvovirus B19
                                          B) Rubella virus
                                          C) Measles virus
                                          D) Roseola virus (HHV-6)


                                          2. The human virome, the collection of viruses that reside in and on the human body, is increasinglyrecognized for its role in health and disease. Which of the following statements regarding the human virome is MOST accurate?

                                          A) Bacteriophages, viruses that infect bacteria, are a significant component of the human gut virome.
                                          B) The human virome is largely independent of the host's immune status.
                                          C) The composition of the human virome is relatively stable over time and is not influenced by environmental factors.
                                          D) The human virome is primarily composed of pathogenic viruses that cause acute infections.


                                          3. A foodborne outbreak is suspected after several individuals who attended a potluck dinner develop nausea, vomiting, and abdominal cramps within 1-6 hours of eating. No fever or diarrhea is reported. The MOST likely bacterial toxin involved is:

                                          A) Staphylococcal enterotoxin
                                          B) Botulinum toxin
                                          C) Shiga toxin
                                          D) Clostridium perfringens enterotoxin


                                          4. A patient with a history of travel to a rural area develops a febrile illness with myalgias and thrombocytopenia. Laboratory testing reveals the presence of morulae within circulating leukocytes. The MOST likely diagnosis is:

                                          A) Anaplasmosis
                                          B) Lyme disease
                                          C) Babesiosis
                                          D) Ehrlichiosis


                                          5. A research laboratory is investigating the mechanisms of antiviral drug resistance. They are studying a herpes simplex virus strain that has developed resistance to acyclovir. The MOST common mechanism of acyclovir resistance in HSV involves mutations in the gene encoding:

                                          A) Viral DNA polymerase
                                          B) Viral glycoprotein D
                                          C) Viral protease
                                          D) Viral thymidine kinase


                                          Solutions:

                                          Question # 1
                                          Answer: A
                                          Question # 2
                                          Answer: A
                                          Question # 3
                                          Answer: A
                                          Question # 4
                                          Answer: D
                                          Question # 5
                                          Answer: D

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