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Updated: May 30, 2026

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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. The end of the initial phase of HH treatment is considered when the serum ferritin decreases to between 20 and
50 ng/mL.
What is a typical finding for determining the endpoint for the initial or iron-depletion phase of treatment for hereditary hemochromatosis (HH)?

A) The transferrin saturation drops below 20%
B) The serum iron falls to below 35 g/dL.
C) The serum ferritin decreases to between 20 and 50 ng/mL
D) The hepatic iron index returns to normal


2. Whole blood glucose values are lower than plasma glucose values. For this reason, point-of-care whole blood glucose meters are programmed to correct the value before presenting the result; therefore, the whole blood glucose meter result correlates to serum or plasma results.
Whole blood glucose values are ____________ plasma glucose values.

A) Greater than
B) Equal to
C) Lower than


3. The term affinity refers to the strength of attraction between a single antigenic determinant and a corresponding antigen binding site. The term avidity refers to the total strength of the attraction between an antibody and a multivalent antigen. The reaction between an IgM molecule (which has 10 antigen binding sites), and a multivalent antigen is therefore much stronger than that of an IgG antibody (which has only 2 antigen binding sites).
Avidity is best described by which of the following statements:

A) The strength with which multivalent antigens and antibodies bind
B) The speed with which an antigen-antibody reaction occurs
C) The strength with which red cells agglutinate
D) The strength with which univalent antigens and antibodies bind


4. HbA1C is the recommended test for monitoring diabetic carbohydrate management. Microalbuminuria, low concentrations of urinary albumin, is measured to detect early renal impairment, at a stage where it is reversible with treatment.
What is the role of microalbuminuria testing?

A) Monitor diabetic patient carbohydrate management
B) Detect small urinary concentrations of albumin before there is irreparable renal damage
C) Diagnose renal failure in a type 1 diabetic patient
D) Detect small-sized urinary albumin molecules in early renal disease


5. DAT ( Direct Antiglobulin Test ).
When AHG or Coombs serum is used to demonstrate that red cells are antibody coated in vivo, the procedure is termed:

A) Hemagglutination technique
B) Direct technique
C) Indirect technique
D) Hemolysis technique


Solutions:

Question # 1
Answer: C
Question # 2
Answer: C
Question # 3
Answer: A
Question # 4
Answer: B
Question # 5
Answer: A

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